John R. Vane (1927–2004)

In memory of Professor John R. Cameron (1922-2005)

John R . Ortaldo , and Ronald

In contrast to the several antigenic markers identified on murine natural killer (NK) 1 cells (1-3), human NK cells have so far been characterized only by surface properties and receptors (4, 5) that do not allow discrimination from many other peripheral blood mononuclear cells. Detection of human NK cells is therefore largely based on the measurement of in vitro cytolytic reactivity against ce...

Aspirin-induced asthma: a tribute to John Vane as a source of inspiration.

Aspirin-induced asthma is a distinct clinical syndrome consisting of inflammation, characterized by chronic eosinophilic rhinosinusitis with asthma and often nasal polyposis. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate asthma, resulting in violent attacks. This is the hallmark of the clinical syndrome as explained by the cyclooxygenase theory. This theory, which i...

Metrics Thermostat by John R . Hauser

thank the managers and product development teams who worked with MIT to collect detailed metrics, covariates, and profit measures for the products that they launched. This paper has benefited from pres-analyzed in the primary application in this paper and performed many of the initial analyses. Thanks also to Arpita Majumder, who helped with the data analysis and who collected the data for the ...

John R. Rice: Mathematical Software Pioneer

John Rischard Rice is one of the founders of mathematical software as a distinct scholarly community. Trained in mathematics he spent four decades in Purdue University’s Department of Computer Sciences. During the 1970s, he convened a series of seminal conferences on the topic and established ACM Transactions on Mathematical Software, which he edited for many years. Rice led development of the ...